Yes. That is true.
Nibbatti lakkhana is basically the blueprint for the building up of any sankata. One is born with a blueprint, but IT CAN BE CHANGED.
As Johnny said, it can be changed by changing one’s gati. This works not only for one’s own body (part of the rupakkhandha or the matter aggregate), but also for one’s thoughts (which have the other four mental kandhas). This is a good meditation topic and one can get deeper into the subject.
Just take one’s body. Even though one will not be able to change the basic features like skin color, height, etc, one will be definitely able to change one’s health, including the brain function (and avoid diseases like Alzeimer’s). I know this by experience. Even though it is hard to get rid of my back problems (I always think about the fact that the Buddha himself had back problems; so such bad vipaka are definitely hard for us to avoid), I am in better condition than I was even 15 20 years ago. I used to take sleeping pills (not strong ones, just mild ones) when I was working. I have not taken one for many years now. I hardly get a headache or flu even though I have never taken a “flu shot”. These are small things, but they make a big difference in one’s state of mind and well being.
Even mental aggregates, one should be able to see the difference after starting on the Path for a few months. You don’t react to things the same way. Your life becomes much more simple, and less burdened.
Each thought is a sankata. A thought arises due to an external stimulus, and those initial thoughts (mano sankhara) depend TOTALLY on one’s gati. And the way to change one’s gati is to change one’s vaci sankhara (especially the part of talking to oneself) just after realizing what those initial and automatic mano sankhara are. I have discussed this in several recent posts. This is the basis of Anapana and Satipatthana meditation.