Hi Lal,
A puthujjana who has not been exposed to the Tilakkhana would not see the worthlessness of worldly things, not even to mention the danger of them. But I believe most people would have in some point of their lives experienced a sense of emptiness and loneliness after or even while enjoying sense pleasures. And because they are not exposed to Buddha Dhamma, they continue to do more of those worldly things which they think can ‘fix’ their problems. But very often they would end up in greater disappointment. They do feel suffering or at least a sense of unsatisfactoriness that lies behind these sense pleasures. But they couldn’t quite make out the reason for such feelings. Instead of finding a more fundamental approach to rectify their issues, they just find another sense pleasure to fill in the void in their heart. Is it appropriate to observe this phenomenon using the doctrine of Udayavaya nana and viparinama dukkha, which are essentially the DNA of the Annica nature?
We often forget that suffering is our best teacher. It is like the entrance ticket to Nibbana.